Glaucoma is an eye problem that affects the retina and leads to permanent blindness if not treated in initial stages. These are established with diverse and complex characteristics as compared to each other for instance the optical coherence tomography (OCT), the fundus photography, the X-ray computed-tomography (CT) image, the magnetic-resonance imaging (MRI), the positron-emission tomography image, the digital-mammography, the ultrasound image, the dermoscopy image, the computed-radiography image etc., are associated with the hospital information and used widely in the clinical diagnosis. Medical imaging and diagnostic radiology plays a vital role in public health worldwide and has become one of the major research topics in recent years. It promotes the e-health field at the retinal level and employed as the decision support system by the young doctors.ĭiagnostic medical imaging modality or computer-aided diagnosis (CAD) is a non-invasive practice that gives an insight of different parts of the body in order to support the diagnosis, detection, and treatment of diseases. The proposed system has shown the higher correlated result of 92.59% sensitivity with the senior most ophthalmologists. The average sensitivity, accuracy, and specificity of the proposed system are 87, 79 and 72%, respectively, on the Armed Forces Institute of Ophthalmology dataset when correlated with clinical annotations and CDR computer generated values. Based on calculated CDRs, the system classifies the subject as normal or glaucomatous.

A novel criterion for horizontal/flat cup diameter based on the average RPE break points is proposed. The method uses both the ILM layer and RPE breakpoints for a cup and disc calculation, respectively. During RPE segmentation, a new ‘centroid based thresholding’ method is proposed to remove extended ILM regions.

A new colour channels mean based quality assessment step is applied to segment out ILM layer for different quality images. A novel method for extraction of the inner limiting membrane (ILM) and retinal pigment epithelium (RPE) layers from optical coherence tomography scans is proposed. Glaucoma is a blindness causing eye disease if not treated in time and caused by the increase in the cup-to-disc region (CDR). IET Generation, Transmission & Distribution.IET Electrical Systems in Transportation.IET Cyber-Physical Systems: Theory & Applications.IET Collaborative Intelligent Manufacturing.CAAI Transactions on Intelligence Technology.

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